Resurrecting a broken genome

Resurrecting melancholia.

OBJECTIVE To define melancholia as a distinct mood disorder, identified by unremitting depressed mood, vegetative dysfunction, and psychomotor disturbances, verifiable by neuroendocrine tests, and treatable by electroconvulsive therapy and tricyclic antidepressants. METHOD A review of the literature of two centuries finds descriptions of severe mood disorders, either depression or mania or ci...

A Broken Metallic Tracheostomy Tube

Resurrecting dead-water phenomenon

We revisit experimental studies performed by Ekman on dead-water (Ekman, 1904) using modern techniques in order to present new insights on this peculiar phenomenon. We extend its description to more general situations such as a three-layer fluid or a linearly stratified fluid in presence of a pycnocline, showing the robustness of dead-water phenomenon. We observe large amplitude nonlinear inter...

Ashapuri Resurrecting a Medieval Temple Site 24

Resurrecting the Dead (Molecules)

Biological molecules, like organisms themselves, are subject to genetic drift and may even become "extinct". Molecules that are no longer extant in living systems are of high interest for several reasons including insight into how existing life forms evolved and the possibility that they may have new and useful properties no longer available in currently functioning molecules. Predicting the se...